1
as in rebellious
given to resisting authority or another's control
refractory players will be ejected from the game
Synonyms & Similar Words
Relevance
Antonyms & Near Antonyms
2
as in stubborn
given to resisting control or discipline by others
believing that rules are only for other people, he's been refractory virtually his entire life
Synonyms & Similar Words
Antonyms & Near Antonyms
Example Sentences
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Recent Examples of refractory
This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA.
—
Kansas City Star, 13 May 2024
Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study.
—Meghana Keshavan, STAT, 15 Apr. 2024
All of the children had rare, relapsed or refractory cancers and were running out of treatment options.
—Michelle Marchante, Miami Herald, 11 Apr. 2024
Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients.
—Damian Garde, STAT, 13 Dec. 2023
See All Example Sentences for refractory
Kansas City Star, 13 May 2024
Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study.
—Meghana Keshavan, STAT, 15 Apr. 2024
All of the children had rare, relapsed or refractory cancers and were running out of treatment options.
—Michelle Marchante, Miami Herald, 11 Apr. 2024
Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients.
—Damian Garde, STAT, 13 Dec. 2023
See All Example Sentences for refractory
Recent Examples of Synonyms for refractory
Adjective
-
From director James DeMonaco, creator of The Purge franchise, actor-comedian Davidson plays Max in The Home, a rebellious twenty-something sentenced to community service at a quiet retirement home.—
Andreas Wiseman,
Deadline,
10 July 2025
-
The story follows rebellious young demigod Ne Zha, who wrestles with his powers and the threat of humanity’s destruction.—
Escher Walcott,
People.com,
9 July 2025
Adjective
-
But earth sign parents can also lean toward being stubborn and strict, which may cause friction during a stand off or while navigating discipline or tough conversations.—
Kara Nesvig,
Parents,
15 July 2025
-
If using for very stubborn stains, use Oxy Bleach powder, which will be gentler and less destructive.—
Daley Quinn,
Southern Living,
14 July 2025
Adjective
-
The country is currently led by former rebel commander Ahmed al-Sharaa who was appointed transitional president last March, having acted as its de-facto leader following Al-Assad’s flight to Russia.—
Melanie Goodfellow,
Deadline,
16 July 2025
-
The president led 15,000 federalized militiamen from Virginia, Maryland, New Jersey, and Pennsylvania into the west—though no rebel army materialized to oppose them.—
Time,
Time,
2 July 2025
Adjective
-
This version of it will be complex, with significant power wielded by the United States and China but with major roles for other players, including an increasingly autonomous Europe, a recalcitrant Russia, and an ever more powerful India.—
REBECCA LISSNER,
Foreign Affairs,
24 June 2025
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Pulled along by Valérie like a recalcitrant puppy, Richard sets off on a quest to find the missing man, who may have ties to the Sicilian Mafia.—
The New Yorker,
New Yorker,
25 June 2025
Adjective
-
On Monday, asked about the poll proposal at an unrelated event, Adams was defiant.—
Oren Oppenheim,
ABC News,
14 July 2025
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Trump's defiant response in Butler, Penn., may have fueled his big Election Day gains among male voters.—
Susan Page,
USA Today,
11 July 2025
Adjective
-
That law permitted the use of low-THC cannabis, then defined as cannabis with no more than 0.5 percent THC and at least 10 percent CBD, for patients with intractable epilepsy.—
Alonzo Martinez,
Forbes.com,
2 July 2025
-
If the sticking points become intractable, someone—namely Trump—may have to step in with a bullhorn and a bullying menace.—
Philip Elliott,
Time,
1 July 2025
Adjective
-
These arachnids suck juices from the tomato plants and seemingly all of a sudden build large uncontrollable populations.—
Tom MacCubbin,
The Orlando Sentinel,
5 July 2025
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Despite months of meticulous planning, there will always be uncontrollable variables that require monitoring..—
Andrew Paul,
Popular Science,
3 July 2025
Adjective
-
Florent, the restaurant, stayed open until 2008, when the rent became unmanageable; the building sold a few years later for $8.6 million.—
Christopher Bonanos,
Curbed,
11 July 2025
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The most common reasons revolve around work-life balance, a lack of support and an unmanageable workload.—
Drew Gerber,
Forbes.com,
20 June 2025
Cite this Entry
“Refractory.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractory. Accessed 22 Jul. 2025.
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