syndrome

noun

syn·​drome ˈsin-ˌdrōm How to pronounce syndrome (audio)
also
-drəm How to pronounce syndrome (audio)
1
: a group of signs and symptoms that occur together and characterize a particular abnormality or condition
2
: a set of concurrent things (such as emotions or actions) that usually form an identifiable pattern

Did you know?

Combining its two Greek roots, syndrome means basically "running together". So when diagnosing a condition or disease, doctors tend to look for a group of symptoms existing together. As long as a set of symptoms remains mysterious, it may be referred to as a specific syndrome. But if that name is used for a while, it may become the condition's permanent name, even after an underlying cause has been found. So today we have Down syndrome, acquired immune deficiency syndrome, Asperger's syndrome, carpal tunnel syndrome, chronic fatigue syndrome, Tourette's syndrome, sick building syndrome, and many more. And since mental conditions often turn out to have physical causes, syndrome is used in psychology as well as in medicine.

Examples of syndrome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These tests are particularly valuable for identifying ultra-rare genetic conditions like Marbach-Schaaf syndrome. Lydia Patrick, MSNBC Newsweek, 19 July 2025 About 10% of people with metastatic NSCLC experience a paraneoplastic syndrome. Carrie Madormo, Health, 18 July 2025 How preventing the superhero syndrome—over-dependance on one leader or top performer—can push your employees to grow. Maria Gracia Santillana Linares, Forbes.com, 15 July 2025 Venus Williams said in 2011 she had been diagnosed with Sjögren’s syndrome, an energy-sapping auto-immune disease that can cause joint pain. Howard Fendrich, Chicago Tribune, 11 July 2025 See All Example Sentences for syndrome

Word History

Etymology

New Latin, from Greek syndromē combination, syndrome, from syn- + dramein to run — more at dromedary

First Known Use

1541, in the meaning defined at sense 1

Time Traveler
The first known use of syndrome was in 1541

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Cite this Entry

“Syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/syndrome. Accessed 22 Jul. 2025.

Kids Definition

syndrome

noun
syn·​drome ˈsin-ˌdrōm How to pronounce syndrome (audio)
: a group of signs and symptoms that occur together and characterize a particular abnormality or condition

Medical Definition

syndrome

noun
syn·​drome
ˈsin-ˌdrōm also -drəm
: a group of signs and symptoms that occur together and characterize a particular abnormality

More from Merriam-Webster on syndrome

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