genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The clinical stage genome editing company plunged 45% after pausing patient dosing and screening for its MAGNITUDE and MAGNITUDE-2 Phase 3 clinical trials. Scott Schnipper, CNBC, 27 Oct. 2025 Researchers at the tech giant created DeepSomatic, a new open-source AI model that helps scientists analyze cancer genomes more quickly and accurately. Jeremy Kahn, Fortune, 21 Oct. 2025 In this op-ed, Andrew Hessel, cofounder of the Human Genome Project–write, argues that genome writing is humanity’s next great moonshot, outlining how DNA synthesis could transform biology, medicine, and industry. Big Think, 20 Oct. 2025 This part of the study provided the first direct functional proof that mutations within the phage genome can permanently silence its ability to reactivate. New Atlas, 16 Oct. 2025 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 29 Oct. 2025.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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