depolarized; depolarizing; depolarizes

transitive verb

1
: to cause to become partially or wholly unpolarized
2
: to prevent or remove polarization of (something, such as a particle (see particle sense 3) or dry cell)
After all, if a positive muon managed to capture one of the many electrons that are free to move about in graphite, the electron could easily depolarize (mess up the spin of) the muon so that they would not all be doing the same thing in lockstep. Leon Lederman et al.
3
physiology : to cause (a muscle or nerve cell) to undergo depolarization
In order to establish whether or not this type of capacitor discharge would depolarize the entire heart, it was tested as a cardiac defibrillator. Bernard Lown et al.

intransitive verb

physiology
: to undergo depolarization
Smooth muscle cells in small arteries depolarize and contract in response to increased intravascular pressure. Joseph E. Brayden and Mark T. Nelson

Examples of depolarize in a Sentence

Recent Examples on the Web
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Or journalists could report work by the House Select Committee on the Modernization of Congress, bipartisan insiders who recommend ways to depolarize Congress. Chicago Tribune, 1 Apr. 2025 Measuring heart rate is the easier task, as the cardiac tissue produces obvious electrical signals when the muscles depolarize and repolarize to produce each heartbeat. IEEE Spectrum, 3 Feb. 2025

Word History

First Known Use

1814, in the meaning defined at sense 1

Time Traveler
The first known use of depolarize was in 1814

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Cite this Entry

“Depolarize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/depolarize. Accessed 22 Apr. 2025.

Medical Definition

depolarize

verb
de·​po·​lar·​ize
depolarized or British depolarised; depolarizing or British depolarising

transitive verb

: to cause (a muscle or nerve cell) to undergo depolarization
In order to establish whether or not this type of capacitor discharge would depolarize the entire heart, it was tested as a cardiac defibrillator. Bernard Lown et al., The Journal of the American Medical Association

intransitive verb

: to undergo depolarization
Smooth muscle cells in small arteries depolarize and contract in response to increased intravascular pressure. Joseph E. Brayden and Mark T. Nelson, Science
depolarizer noun
Last Updated: - Updated example sentences
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