toxicity

noun

tox·​ic·​i·​ty täk-ˈsi-sə-tē How to pronounce toxicity (audio)
plural toxicities
: the quality or state of being toxic: such as
a
: the quality, state, or relative degree of being poisonous
measuring the toxicity level of the soil
The toxicity of some chemical agents degrades significantly over time, so it is unclear how lethal the stockpiles are.David S. Cloud
Administering a cocktail of drugs would dilute the toxicities of the different drugs and minimize the development of viral resistance to them.Rudy M. Baum and Ron Dagani
b
: an extremely harsh, malicious, or harmful quality
In the past few days, I've tuned in to C-SPAN to watch a number of the televised Senate debates, which illustrate all too vividly the toxicity of an uncivil tongue.Connie Schultz
In much of the ensuing commentary, court watchers worried that the justices' soaring rates of written dissents, nasty and personal attacks and scathing remarks read aloud from the bench bespeak a new toxicity in Supreme Court discourse.Dahlia Lithwick

Did you know?

Toxicity is often a relative thing; in the words of a famous old saying, "The dose makes the poison". Thus, it's possible to die from drinking too much water, and lives have been saved by tiny doses of arsenic. Even though botulinum toxin is the most toxic substance known, it's the basic ingredient in Botox, which is injected into the face to get rid of wrinkles. With some poisons, mere skin contact can be lethal; others are lethal when breathed into the lungs in microscopic amounts. To determine if a chemical will be officially called a poison, researchers often use the "LD50" test: If 50 milligrams of the substance for every kilogram of an animal's body weight results in the death of 50% of test animals, the chemical is a poison. But there are problems with such tests, and toxicity remains a very individual concept.

Examples of toxicity in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
At times, the division has created toxicity in the overall community, making some hardcore fans feel the need to devote their energy to just one act above all else. Brittany Spanos, Rolling Stone, 28 Oct. 2025 Too much vitamin D can lead to toxicity, also known as vitamin D hypervitaminosis. Sherri Gordon, Health, 28 Oct. 2025 The cause and manner of death in the cases included accidental drownings, a suicide, drug toxicity, blunt force trauma and cardiovascular disease, according to the medical examiner data. Dalia Faheid, CNN Money, 27 Oct. 2025 Today, many women are offered drugs designed to target specific cancer cell mutations, sparing them unnecessary toxicity. Lauryn Higgins, Flow Space, 21 Oct. 2025 See All Example Sentences for toxicity

Word History

First Known Use

1873, in the meaning defined above

Time Traveler
The first known use of toxicity was in 1873

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Cite this Entry

“Toxicity.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/toxicity. Accessed 2 Nov. 2025.

Medical Definition

toxicity

noun
tox·​ic·​i·​ty täk-ˈsis-ət-ē How to pronounce toxicity (audio)
plural toxicities
: the quality, state, or relative degree of being toxic or poisonous

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