refractoriness
noun
                                                                                                                            
                                                            re·frac·to·ri·ness
                    
                                                                                                              
                                                                                                                                  ri-ˈfrak-t(ə-)rē-nəs 
                                                      
                                                          
            
                                
              
          
                                                      : the insensitivity to further immediate stimulation that develops in irritable and especially nervous tissue as a result of intense or prolonged stimulation                                      
                
                    
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  Merriam-Webster unabridged




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