prophylaxis

noun

pro·​phy·​lax·​is ˌprō-fə-ˈlak-səs How to pronounce prophylaxis (audio)
 also  ˌprä-
plural prophylaxes ˌprō-fə-ˈlak-ˌsēz How to pronounce prophylaxis (audio)
 also  ˌprä-
: measures designed to preserve health (as of an individual or of society) and prevent the spread of disease

Did you know?

In Greek, phylax means "guard", so prophylactic measures guard against disease by taking action ahead of time. Thus, for example, before the polio vaccine became available, prophylaxis against polio included avoiding crowds and public swimming pools. These days a well-known kind of prophylactic is used to prevent sexually transmitted diseases; but prophylactic measures only work when people use them.

Examples of prophylaxis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
People who have been exposed are advised to get post-exposure prophylaxis, which includes a dose of human rabies immune globulin (HRIG) and a four-dose series of rabies vaccine. Beth Mole, ArsTechnica, 13 Aug. 2025 Doctors will typically prescribe a post-exposure prophylaxis (PEP) with a 200-milligram dose of the antibiotic doxycycline to be taken within 72 hours of a high-risk tick bite, epidemiologists told Fox News Digital. Amy McGorry, FOXNews.com, 29 July 2025 In addition to such highly effective barrier methods of prevention, there are newer medicines—like pre-exposure prophylaxis, or PrEP, and PEP for post-exposure protection. Victoria Uwumarogie, Essence, 21 July 2025 Post-exposure prophylaxis is offering someone a drug or vaccine after they are exposed to a germ, to reduce the chance they will be infected or develop severe disease. Sarah Lynch Baldwin, CBS News, 17 June 2025 See All Example Sentences for prophylaxis

Word History

Etymology

borrowed from New Latin, from Greek prophylak-, stem of prophylássein "to keep guard before a place, be on guard, (middle voice) to be on one's guard against, take precautions against" (from pro- pro- entry 1 + phylássein "to keep watch on, guard, preserve," derivative of phylak-, phýlax "guard, guardian, protector") + -sis -sis — more at phylactery

First Known Use

1683, in the meaning defined above

Time Traveler
The first known use of prophylaxis was in 1683

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Cite this Entry

“Prophylaxis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prophylaxis. Accessed 23 Aug. 2025.

Medical Definition

prophylaxis

noun
pro·​phy·​lax·​is -ˈlak-səs How to pronounce prophylaxis (audio)
plural prophylaxes -ˈlak-ˌsēz How to pronounce prophylaxis (audio)
: measures designed to preserve health and prevent the spread of disease : protective or preventive treatment
prophylaxis against viral diseases
a paste containing fluorine for dental prophylaxis

More from Merriam-Webster on prophylaxis

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