proband
noun
pro·band
ˈprō-ˌband 
prō-ˈband
: an individual affected with a disorder who is the first subject in a study (as of a genetic character in a family lineage)
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“Proband.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/proband. Accessed 3 Nov. 2025.
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proband
noun
pro·band
ˈprō-ˌband
: an individual affected with a disorder who is the first subject in a study (as of a genetic character in a family lineage)
called also propositus
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