1
: of inferior grade or quality
2
: being near that extreme of a specified range which is lowest, least intense, least serious, or least competent
a low-grade fever
a low-grade infection

Examples of low-grade in a Sentence

plumbing fixtures that were made out of low-grade materials
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These results suggest that these immune proteins might be contributing to the low-grade inflammation that accompanies aging. Viviane Callier, Scientific American, 20 Oct. 2025 Some of the tumors on my abdominal wall and on my ovary had come back as stage 3 low-grade ovarian cancer. Wendy Grossman Kantor, PEOPLE, 17 Oct. 2025 Not today, when regional lenders were under severe pressure as low-grade anxiety builds about the prospect of credit hiccups and perhaps some tightening in parts of the wholesale funding complex. Michael Santoli, CNBC, 16 Oct. 2025 And certain vaccines can trigger brief, low-grade fevers as the immune system builds protection. Daryl Austin, USA Today, 14 Oct. 2025 See All Example Sentences for low-grade

Word History

First Known Use

1877, in the meaning defined at sense 1

Time Traveler
The first known use of low-grade was in 1877

Browse Nearby Words

Cite this Entry

“Low-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/low-grade. Accessed 23 Oct. 2025.

Kids Definition

low-grade

adjective
ˈlō-ˈgrād
1
: of poor grade or quality
2
: being near that end of a range which is lowest, weakest, or least able
a low-grade fever

Medical Definition

low-grade

adjective
: being near that extreme of a specified range which is lowest, least intense, or least competent
a low-grade fever
a low-grade infection
compare high-grade
Last Updated: - Updated example sentences
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