first-line
adjective
: being the preferred, standard, or first choice
first-line treatment of tuberculosis
compare second-line
Examples of first-line in a Sentence
surgery is usually not considered a first-line treatment for this type of cancer
Recent Examples on the Web
His play has electrified this franchise in a big way and helps make up for the fact that this team doesn’t have an elite first-line center.
—
Shayna Goldman, New York Times, 9 Oct. 2025
The administrator provides first-line leadership to a team of staff working the Quality Assurance, Correspondence and Automatic Call Distribution phone line workloads.
—Sacbee.com, 9 Oct. 2025
Her main concern is when they are offered as a first-line solution.
—Alyssa Goldberg, USA Today, 10 Sep. 2025
And they are never used as a first-line therapy, only as a last resort.
—Dr. Sanjay Gupta, CNN Money, 2 Sep. 2025
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Shayna Goldman, New York Times, 9 Oct. 2025
The administrator provides first-line leadership to a team of staff working the Quality Assurance, Correspondence and Automatic Call Distribution phone line workloads.
—Sacbee.com, 9 Oct. 2025
Her main concern is when they are offered as a first-line solution.
—Alyssa Goldberg, USA Today, 10 Sep. 2025
And they are never used as a first-line therapy, only as a last resort.
—Dr. Sanjay Gupta, CNN Money, 2 Sep. 2025
See All Example Sentences for first-line
Cite this Entry
“First-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/first-line. Accessed 4 Nov. 2025.
Copy CitationMedical Definition
first-line
adjective
: being the preferred, standard, or first choice
first-line treatment of advanced breast cancer
compare second-line
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