clonidine
noun
clo·ni·dine
ˈklä-nə-ˌdēn 
ˈklō-
ˈklō-
-ˌdīn
: an antihypertensive drug C9H9Cl2N3 used especially to treat essential hypertension, to prevent migraine headache, and to diminish opioid and nicotine withdrawal symptoms
Examples of clonidine in a Sentence
Recent Examples on the Web
This includes hormonal therapy like oral, transdermal, topical and vaginal ring treatments, along with non-hormonal therapy, such as antidepressants, clonidine, gabapentin and ospemifene.
—
Lauryn Higgins, Flow Space, 24 Jan. 2025
Among the options: hormone replacement therapy, low-dose selective serotonin reuptake inhibitors (SSRIs), gabapentin, clonidine, and fezolinetant.
—Angela Haupt, TIME, 21 June 2024
Some case studies indicate that kratom may have mechanisms similar to opioid withdrawal treatments like clonidine.
—Claire Bugos, Verywell Health, 3 Aug. 2023
Hormone therapy, clonidine pills or patches, low-dose antidepressants, and vaginal estrogen are among some of the treatments, per the Mayo Clinic, yet experts say many people don’t know about the benefits or drawbacks of treatment.
—Alexa Mikhail, Fortune, 1 Feb. 2023
My blood pressure still fluctuated, and I was prescribed 5 mg of clonidine to take as emergency medication for anything over 180/100.
—Dr. Keith Roach, oregonlive, 1 July 2022
Medication options for opioids include methadone, buprenorphine, naltrexone, or clonidine.
—Sara Lindberg, SELF, 1 Nov. 2021
Although non-prescription melatonin is by far the most popular, some children are prescribed epilepsy drugs, sedatives, alpha agonists such as clonidine or antidepressants such as trazodone, depending on the nature of their problem.
—Claudia Wallis, Scientific American, 18 Nov. 2017
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Lauryn Higgins, Flow Space, 24 Jan. 2025
Among the options: hormone replacement therapy, low-dose selective serotonin reuptake inhibitors (SSRIs), gabapentin, clonidine, and fezolinetant.
—Angela Haupt, TIME, 21 June 2024
Some case studies indicate that kratom may have mechanisms similar to opioid withdrawal treatments like clonidine.
—Claire Bugos, Verywell Health, 3 Aug. 2023
Hormone therapy, clonidine pills or patches, low-dose antidepressants, and vaginal estrogen are among some of the treatments, per the Mayo Clinic, yet experts say many people don’t know about the benefits or drawbacks of treatment.
—Alexa Mikhail, Fortune, 1 Feb. 2023
My blood pressure still fluctuated, and I was prescribed 5 mg of clonidine to take as emergency medication for anything over 180/100.
—Dr. Keith Roach, oregonlive, 1 July 2022
Medication options for opioids include methadone, buprenorphine, naltrexone, or clonidine.
—Sara Lindberg, SELF, 1 Nov. 2021
Although non-prescription melatonin is by far the most popular, some children are prescribed epilepsy drugs, sedatives, alpha agonists such as clonidine or antidepressants such as trazodone, depending on the nature of their problem.
—Claudia Wallis, Scientific American, 18 Nov. 2017
Cite this Entry
“Clonidine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clonidine. Accessed 4 Nov. 2025.
Copy CitationMedical Definition
clonidine
noun
clo·ni·dine
ˈklän-ə-ˌdēn
ˈklōn-
ˈklōn-
-ˌdīn
: an antihypertensive drug used in the form of its hydrochloride C9H9Cl2N3·HCl especially to treat essential hypertension, to prevent migraine headache, and to diminish opiate withdrawal symptoms
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