antihistamine
noun
an·ti·his·ta·mine
ˌan-tē-ˈhi-stə-ˌmēn 
-mən,
ˌan-tī-
: any of various compounds that counteract histamine in the body and that are used for treating allergic reactions (such as hay fever) and cold symptoms
antihistamine
adjective
Examples of antihistamine in a Sentence
Recent Examples on the Web
The government also alleges Hemani used and sold promethazine, an antihistamine used to treat allergies and motion sickness that can boost an opioid high, and used cocaine, although he was prosecuted based on his marijuana use.
—
Maureen Groppe, USA Today, 20 Oct. 2025
Grab your bottle of antihistamine.
—Frederick Dreier, Outside, 20 Oct. 2025
However, if the obstruction is from congestion, your best bet may be a decongestant or antihistamine.
—Bestreviews, Mercury News, 14 Oct. 2025
Treatments include long-lasting antihistamines, anti-itch creams, and topical or oral corticosteroids.
—Maggie Ryan, Flow Space, 1 Oct. 2025
See All Example Sentences for antihistamine
Examples are automatically compiled from online sources to
show current usage.
Read More
Opinions expressed in the examples do not represent those of Merriam-Webster or its editors.
Send us feedback.
Maureen Groppe, USA Today, 20 Oct. 2025
Grab your bottle of antihistamine.
—Frederick Dreier, Outside, 20 Oct. 2025
However, if the obstruction is from congestion, your best bet may be a decongestant or antihistamine.
—Bestreviews, Mercury News, 14 Oct. 2025
Treatments include long-lasting antihistamines, anti-itch creams, and topical or oral corticosteroids.
—Maggie Ryan, Flow Space, 1 Oct. 2025
See All Example Sentences for antihistamine
Cite this Entry
“Antihistamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antihistamine. Accessed 30 Oct. 2025.
Copy CitationKids Definition
antihistamine
noun
an·ti·his·ta·mine
ˌant-i-ˈhis-tə-ˌmēn
-mən,
ˌan-ˌtī-
: any of various drugs used for treating allergic reactions and cold symptoms
Medical Definition
antihistamine
1 of 2 adjective
an·ti·his·ta·mine
ˌant-i-ˈhis-tə-ˌmēn, ˌan-ˌtī-, -mən
: tending to block or counteract the physiological action of histamine
human blood lacks antihistamine activity
antihistamine
2 of 2 noun
: any of various compounds that oppose the actions of histamine and are used especially for treating allergic reactions (as hay fever), cold symptoms, and motion sickness
Love words? Need even more definitions?
Merriam-Webster unabridged
Share