testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn How to pronounce testosterone (audio)
1
: a hormone that is a hydroxy steroid ketone C19H28O2 produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters
2
: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Elsewhere in the book, Sheen writes about his public meltdown amid his firing from his hit CBS sitcom, blaming his rage on testosterone cream. Maureen Lee Lenker, Entertainment Weekly, 10 Sep. 2025 Commonly used to treat vaginal atrophy during menopause, DHEA is a precursor to testosterone and, in some women, has been shown to elevate testosterone levels. Sam Manzella, Flow Space, 10 Sep. 2025 The now pastor will undergo proton radiation therapy for seven weeks and take testosterone blockers, as in some cases the hormone can cause the cancer to grow. Demicia Inman, VIBE.com, 4 Sep. 2025 Social media influencers are pressuring boys with harmful messages that equate masculinity with extreme muscle growth and testosterone use. Ashleigh N. Deluca, Parents, 4 Sep. 2025 See All Example Sentences for testosterone

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Time Traveler
The first known use of testosterone was in 1935

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Cite this Entry

“Testosterone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/testosterone. Accessed 14 Sep. 2025.

Kids Definition

testosterone

noun
tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn How to pronounce testosterone (audio)
: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun
tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn How to pronounce testosterone (audio)
: a male hormone that is a crystalline hydroxy steroid ketone C19H28O2 produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron

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