: any of a group of drugs (such as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma
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These drugs include Tylenol (acetaminophen), statins, macrolides, anticonvulsants, antituberculosis medications, and some herbal supplements.
—
Suchandrima Bhowmik, Health, 24 May 2025
For people with elevated LDL who don’t respond sufficiently to statins and are at very high risk for cardiovascular disease, strong cholesterol drugs called PCSK9 inhibitors have been found to reduce elevated Lp(a) levels by 20 to 25%.
—Stacey Colino, Time, 22 May 2025
Three statins—lovastatin, pravastatin and atorvastatin—were rejected by FDA.
—Joshua P. Cohen, Forbes.com, 6 May 2025
These include orlistat, statins, steroids, and thiazide diuretics.1 Interactions may cause supplements or medications to work improperly.
—Brittany Lubeck, Ms, Rdn, Verywell Health, 17 Mar. 2025
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Suchandrima Bhowmik, Health, 24 May 2025
For people with elevated LDL who don’t respond sufficiently to statins and are at very high risk for cardiovascular disease, strong cholesterol drugs called PCSK9 inhibitors have been found to reduce elevated Lp(a) levels by 20 to 25%.
—Stacey Colino, Time, 22 May 2025
Three statins—lovastatin, pravastatin and atorvastatin—were rejected by FDA.
—Joshua P. Cohen, Forbes.com, 6 May 2025
These include orlistat, statins, steroids, and thiazide diuretics.1 Interactions may cause supplements or medications to work improperly.
—Brittany Lubeck, Ms, Rdn, Verywell Health, 17 Mar. 2025
See All Example Sentences for statin
Cite this Entry
“Statin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/statin. Accessed 3 Jun. 2025.
Copy CitationMedical Definition
statin
noun
stat·in
ˈstat-ᵊn 
: any of a group of lipid-lowering drugs (as lovastatin and simvastatin) that function by inhibiting a liver enzyme which controls the synthesis of cholesterol and by promoting the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma
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