sirolimus
noun
si·ro·li·mus
si-ˈrō-li-məs 
: an immunosuppressive drug C51H79NO13 that is a macrocyclic lactone obtained from a soil bacterium of the genus Streptomyces (S. hygroscopicus) and is taken orally especially to prevent rejection of transplanted organs
Sirolimus (also called rapamycin) is a macrolide antibiotic that blocks proliferative responses of lymphocytes to interleukin-2 by inhibiting interleukin-2-mediated signal-transduction events.—
Manuel Pascual et al., The New England Journal of Medicine
Manuel Pascual et al., The New England Journal of Medicinecalled also rapamycin
Note: Sirolimus is often taken in combination with other immunosuppressive drugs (such as cyclosporine) and is marketed under the trademark Rapamune.
Cite this Entry
“Sirolimus.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/sirolimus. Accessed 4 Nov. 2025.
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