sertraline
noun
ser·tra·line
ˈsər-trə-ˌlēn 
: an antidepressant drug C17H17NCl2 administered in the form of its hydrochloride and acting to enhance serotonin activity
Examples of sertraline in a Sentence
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Antidepressants, especially selective serotonin reuptake inhibitors (SSRIs) like fluoxetine (Prozac) or sertraline (Zoloft), are among the most common meds to cause sweating, says Jenkins.
—
Lauryn Higgins, Time, 7 July 2025
Researchers found that combining rhodiola with sertraline led to better outcomes than sertraline alone.6
In one review, a few studies found that rhodiola supplementation may help stabilize mood in some people.
—Brittany Lubeck, Ms, Rdn, Verywell Health, 25 Apr. 2025
Further, the team found differences between different types of SSRI—with escitalopram associated with the fastest rate of cognitive decline, followed by citalopram and sertraline.
—Matt Robison, Newsweek, 25 Feb. 2025
For instance, a patient might be dissuaded from taking paroxetine over sertraline due to a greater short-term risk of weight gain.
—Don Rauf, EverydayHealth.com, 5 July 2024
Selective serotonin reuptake inhibitors fluoxetine and sertraline had the lowest occurrence.
—Annalisa Merelli, STAT, 5 June 2024
For these people, antidepressants such as paroxetine, sertraline and venlafaxine are recommended as alternatives, or as an addition to psychotherapy.
—C. Michael White, The Conversation, 8 Nov. 2023
In an analogous human study in 2016, researchers in Brazil divided 57 adults taking the antidepressant sertraline for moderate to severe depression into two groups: one attended four sessions of aerobic activity a week for 28 days, and the other did not exercise.
—Ferris Jabr, Scientific American, 1 Jan. 2017
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Lauryn Higgins, Time, 7 July 2025
Researchers found that combining rhodiola with sertraline led to better outcomes than sertraline alone.6
In one review, a few studies found that rhodiola supplementation may help stabilize mood in some people.
—Brittany Lubeck, Ms, Rdn, Verywell Health, 25 Apr. 2025
Further, the team found differences between different types of SSRI—with escitalopram associated with the fastest rate of cognitive decline, followed by citalopram and sertraline.
—Matt Robison, Newsweek, 25 Feb. 2025
For instance, a patient might be dissuaded from taking paroxetine over sertraline due to a greater short-term risk of weight gain.
—Don Rauf, EverydayHealth.com, 5 July 2024
Selective serotonin reuptake inhibitors fluoxetine and sertraline had the lowest occurrence.
—Annalisa Merelli, STAT, 5 June 2024
For these people, antidepressants such as paroxetine, sertraline and venlafaxine are recommended as alternatives, or as an addition to psychotherapy.
—C. Michael White, The Conversation, 8 Nov. 2023
In an analogous human study in 2016, researchers in Brazil divided 57 adults taking the antidepressant sertraline for moderate to severe depression into two groups: one attended four sessions of aerobic activity a week for 28 days, and the other did not exercise.
—Ferris Jabr, Scientific American, 1 Jan. 2017
Cite this Entry
“Sertraline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sertraline. Accessed 30 Oct. 2025.
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sertraline
noun
ser·tra·line
ˈsər-trə-ˌlēn
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