sclerosis
noun
scle·ro·sis
sklə-ˈrō-səs 
1
: pathological hardening of tissue especially from overgrowth of fibrous tissue or increase in interstitial tissue
also
: a disease characterized by sclerosis
2
: an inability or reluctance to adapt or compromise
political sclerosis
Examples of sclerosis in a Sentence
Recent Examples on the Web
The researchers measured hippocampal sclerosis (HS)—a severe decline in brain cells and processes in particular areas of the brain linked with dementia and Alzheimer's—in 809 people with available brain autopsies and dietary information.
—
Hannah Millington, MSNBC Newsweek, 7 Aug. 2025
Multiple Sclerosis Multiple sclerosis is a chronic neurological condition caused by inflammatory processes that affect brain and spinal cord function.
—Heidi Moawad, Verywell Health, 31 July 2025
While American pharmaceutical development exhibits signs of institutional sclerosis, China’s system demonstrates the power of aligned incentives, streamlined processes, and strategic coordination between regulatory bodies, research institutions, and industry players.
—Greg Licholai Md, Forbes.com, 25 June 2025
The company expects topline data from the systemic sclerosis trial in the fourth quarter of 2026.
—Quartz Intelligence Newsroom, Quartz, 25 Mar. 2025
See All Example Sentences for sclerosis
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Hannah Millington, MSNBC Newsweek, 7 Aug. 2025
Multiple Sclerosis Multiple sclerosis is a chronic neurological condition caused by inflammatory processes that affect brain and spinal cord function.
—Heidi Moawad, Verywell Health, 31 July 2025
While American pharmaceutical development exhibits signs of institutional sclerosis, China’s system demonstrates the power of aligned incentives, streamlined processes, and strategic coordination between regulatory bodies, research institutions, and industry players.
—Greg Licholai Md, Forbes.com, 25 June 2025
The company expects topline data from the systemic sclerosis trial in the fourth quarter of 2026.
—Quartz Intelligence Newsroom, Quartz, 25 Mar. 2025
See All Example Sentences for sclerosis
Cite this Entry
“Sclerosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sclerosis. Accessed 31 Oct. 2025.
Copy CitationKids Definition
sclerosis
noun
scle·ro·sis
sklə-ˈrō-səs
: an abnormal hardening of a tissue or body part (as arteries or muscles) that occurs in several serious diseases compare multiple sclerosis
Medical Definition
sclerosis
noun
scle·ro·sis
sklə-ˈrō-səs
plural scleroses
-ˌsēz
1
: a pathological condition in which a tissue has become hard and which is produced by overgrowth of fibrous tissue and other changes (as in arteriosclerosis) or by increase in interstitial tissue and other changes (as in multiple sclerosis)
called also hardening
2
: any of various diseases characterized by sclerosis
—usually used in combination
see arteriosclerosis, multiple sclerosis, myelosclerosis
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