Sandhoff's disease
noun
Sand·hoff's disease
ˈsand-ˌhȯfs- 
variants
or Sandhoff disease
: a hereditary disorder of lipid metabolism that is closely related to or a variant of Tay-Sachs disease, typically affects individuals of non-Jewish ancestry, and is characterized by great reduction in or absence of both hexosaminidase A and hexosaminidase B
Cite this Entry
“Sandhoff's disease.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/Sandhoff%27s%20disease. Accessed 30 Oct. 2025.
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