1
: of, relating to, or concerned with the period preceding clinical manifestations
2
: of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry
3
: occurring prior to clinical testing
a preclinical animal study of a new therapy

Examples of preclinical in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The next steps are to continue with preclinical trials to ensure the implant is safe and effective. Paul McClure 23, New Atlas, 23 Feb. 2025 Synthesis and preclinical evaluation of tigilanol tiglate analogs as latency-reversing agents for the eradication of HIV World Health Organization. Joshua Rapp Learn, Discover Magazine, 11 Feb. 2025 May Have Anticancer Effects Some initial preclinical studies (conducted on animals) have shown promise for curcumin's anticancer effects. Amber J. Tresca, Verywell Health, 10 Feb. 2025 The group of experts recommends using two levels of obesity: preclinical and clinical. Melissa Rudy, Fox News, 20 Jan. 2025 See All Example Sentences for preclinical

Word History

First Known Use

1876, in the meaning defined at sense 1

Time Traveler
The first known use of preclinical was in 1876

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Cite this Entry

“Preclinical.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/preclinical. Accessed 10 Mar. 2025.

Medical Definition

preclinical

adjective
1
a
: of, relating to, concerned with, or being the period preceding clinical manifestations
the preclinical stage of diabetes mellitus
b
: occurring prior to a clinical trial
preclinical animal testing to assess a drug's safety
2
: of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry
the preclinical years
specifically : of or relating to the early period of prescribed medical or dental study devoted to the basic sciences (as anatomy, physiology, and pathology)
preclinical studies
3
: of, relating to, or being a science basic to medicine
research in the preclinical sciences
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