polymorphism

noun

poly·​mor·​phism ˌpä-lē-ˈmȯr-ˌfi-zəm How to pronounce polymorphism (audio)
: the quality or state of existing in or assuming different forms: such as
a(1)
: existence of a species in several forms independent of the variations of sex
(2)
: existence of a gene in several allelic forms
also : a variation in a specific DNA sequence
(3)
: existence of a molecule (such as an enzyme) in several forms in a single species
b
: the property of crystallizing in two or more forms with distinct structure
polymorphic adjective
polymorphically adverb

Examples of polymorphism in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The technology scans the entire genome for single nucleotide polymorphisms, or SNPs—the spots where one person’s genome might have a T, while another’s has a C—for associations with human behaviors. Eric Turkheimer, The Atlantic, 13 Oct. 2025 Armed Forces Medical Examiner System scientists, the agency said, also employed mitochondrial DNA analysis, mitochondrial genome sequencing, and nuclear single-nucleotide polymorphism testing. Frank Witsil, Freep.com, 15 July 2025 Lightweight forms of polymorphism can also be applied to IoT cybersecurity, rotating communication protocols and encryption keys, enhancing resilience and being mindful of resources simultaneously. Carlo Tortora Brayda, Forbes.com, 25 June 2025 And within this group, the researchers identified three tiny mutations – known as single-nucleotide polymorphisms (SNPs) – that increased one's chances of being impacted by the kidney and mental health conditions. Bronwyn Thompson, New Atlas, 15 June 2025 See All Example Sentences for polymorphism

Word History

First Known Use

1839, in the meaning defined above

Time Traveler
The first known use of polymorphism was in 1839

Browse Nearby Words

Cite this Entry

“Polymorphism.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polymorphism. Accessed 19 Oct. 2025.

Medical Definition

polymorphism

noun
poly·​mor·​phism ˌpäl-i-ˈmȯr-ˌfiz-əm How to pronounce polymorphism (audio)
: the quality or state of existing in or assuming different forms: as
a(1)
: existence of a species in several forms independent of the variations of sex
(2)
: existence of a gene in several allelic forms
also : a variation in a specific sequence of DNA
(3)
: existence of a molecule (as an enzyme) in several forms in a single species
b
: the property of crystallizing in two or more forms with distinct structure

More from Merriam-Webster on polymorphism

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!