MIS-C
2 of 2abbreviation or noun
ˌem-ˌī-ˌes-ˈsē 
ˈmis-ˈsē
: multisystem inflammatory syndrome in children
The features of MIS-C include signs that the blood vessels and organs are irritated or inflamed.—
Elaine Cox
Elaine CoxThe syndrome appears to be rare, but the Centers for Disease Control and Prevention—which recently dubbed the condition MIS-C or multisystem inflammatory syndrome in children—has expressed alarm about the rapid decline of patients with the illness.—Ariana Eunjung Cha and Chelsea Janes
Ariana Eunjung Cha and Chelsea JanesExamples of misc in a Sentence
Recent Examples on the Web
Emily Kay Votruba, EverydayHealth.com, 28 May 2025
Only five children with MIS-C had received three or more doses.
—Mary Kekatos, ABC News, 14 Mar. 2024
There have also been 12 reported pediatric influenza deaths and 30 reports of MIS-C, a rare complication that typically occurs a month after a COVID infection, the organization added.
—Nicholas Rice, Peoplemag, 17 Dec. 2023
There were no reports of myocarditis or pericarditis (inflammation of the heart and surrounding tissue) or multisystem inflammatory syndrome in children (MIS-C).
—Jon Brodkin, Ars Technica, 13 Sep. 2023
Public health officials in Virginia late last year removed percent positivity, testing data, outbreaks and MIS-C (or multisystem inflammatory syndrome) case information from the dashboard.
—Jenna Portnoy, Washington Post, 2 May 2023
Children who developed multisystem inflammatory syndrome, or MIS-C, are also more vulnerable to long COVID.
—Luke Money, Los Angeles Times, 10 Mar. 2023
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Abbreviation or noun
For instance, pediatric long COVID — also called MIS-C, or multisystem inflammatory syndrome in children — may happen two to six weeks after coronavirus infection and develop even if symptoms are mild or nonexistent.
—Emily Kay Votruba, EverydayHealth.com, 28 May 2025
Only five children with MIS-C had received three or more doses.
—Mary Kekatos, ABC News, 14 Mar. 2024
There have also been 12 reported pediatric influenza deaths and 30 reports of MIS-C, a rare complication that typically occurs a month after a COVID infection, the organization added.
—Nicholas Rice, Peoplemag, 17 Dec. 2023
There were no reports of myocarditis or pericarditis (inflammation of the heart and surrounding tissue) or multisystem inflammatory syndrome in children (MIS-C).
—Jon Brodkin, Ars Technica, 13 Sep. 2023
Public health officials in Virginia late last year removed percent positivity, testing data, outbreaks and MIS-C (or multisystem inflammatory syndrome) case information from the dashboard.
—Jenna Portnoy, Washington Post, 2 May 2023
Children who developed multisystem inflammatory syndrome, or MIS-C, are also more vulnerable to long COVID.
—Luke Money, Los Angeles Times, 10 Mar. 2023
Cite this Entry
“Misc.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/misc. Accessed 4 Nov. 2025.
Copy CitationMedical Definition
MIS-C
abbreviation or noun
ˌem-ˌī-ˌes-ˈsē
ˈmis-ˈsē
: multisystem inflammatory syndrome in children
The medical condition, known as multisystem inflammatory syndrome in children, or MIS-C, is a rare but potentially deadly medical condition typically affecting multiple organs—including the heart, kidneys, brain, among others—that has been detected in children or young adults up to 21 years of age who are believed to have had COVID-19 or been exposed to it, according to the federal Centers for Disease Control.—Andy East, The Republic (Columbus, Indiana)
Andy East, The Republic (Columbus, Indiana)Most children with MIS-C have persistent high fevers for three or more days, but then exhibit a range of symptoms in various combinations reflecting inflammation in multiple organs of the body.—Sandra L. Fenwick, The Boston Globe
Sandra L. Fenwick, The Boston GlobeLove words? Need even more definitions?
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