keratinocyte

noun

ke·​ra·​ti·​no·​cyte kə-ˈra-tə-nə-ˌsīt How to pronounce keratinocyte (audio) ˌker-ə-ˈti- How to pronounce keratinocyte (audio)
plural keratinocytes
: a cell of the epidermis that produces keratin, is formed in the basal epidermal layer above the dermis, divides to produce more keratinocytes, and ultimately migrates into the outer protective layers of the skin and undergoes final differentiation into a corneocyte
keratinocytes gain their strength from fibrous proteins called keratins, which assemble into long, intertwined cables.Steven Lanier McKnight

Examples of keratinocyte in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Of these, seven showed clear anti-aging effects when tested directly on aged human fibroblasts (cells that form connective tissue) and keratinocytes (the major cell type of the outermost layers of the skin) in the lab. New Atlas, 10 Aug. 2025 The outermost layer of skin, known as the epidermis, is made up of a fibrous protein called keratin, which is produced by skin cells called keratinocytes, Dr. Gohara explains. Victoria Moorhouse, Allure, 30 July 2025 This indicates vitamin C stimulates keratinocyte growth and division. Jenny Lehmann, Discover Magazine, 30 June 2025 Overall, Sensitive Skin Soothing Care was conceived to counteract keratinocytes, or skin cells, to reduce sensitivity. Jennifer Weil, WWD, 14 Jan. 2025 Among them, the epidermal growth factor that gets the hero treatment in the brand’s core range; keratinocyte growth factor, which boosts the skin barrier, and interleukin-1 alpha, which aids in firmness. James Manso, Footwear News, 3 Sep. 2019 For example, the program was able to distinguish between keratinocyte carcinomas—the most common human skin cancer—and benign skin growths called seborrheic keratoses. IEEE Spectrum, 25 Jan. 2017

Word History

Etymology

keratin + -o- + -cyte

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of keratinocyte was in 1950

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Cite this Entry

“Keratinocyte.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/keratinocyte. Accessed 14 Sep. 2025.

Medical Definition

keratinocyte

noun
ke·​ra·​ti·​no·​cyte kə-ˈrat-ᵊn-ə-ˌsīt How to pronounce keratinocyte (audio) ˌker-ə-ˈtin- How to pronounce keratinocyte (audio)
: an epidermal cell that produces keratin
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