insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
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According to the United Nations Development Programme, the consumption of microplastics has been linked to serious health issues, such as endocrine disruption, weight gain, insulin resistance, decreased reproductive health and cancer. Jonathan Limehouse, USA Today, 16 May 2025 Normal levels of this biomarker are essential for regulating multiple biological functions, but high levels have been linked to a range of issues including weight gain, insulin resistance, and an elevated risk of developing diabetes. Michael Franco may 15, New Atlas, 15 May 2025 Poor sleep continuity has been linked to a higher risk for AFib, heart attack, high blood pressure and greater insulin resistance. American Heart Association News, Boston Herald, 27 Apr. 2025 And there are lots of questions about how other health conditions, including cardiovascular disease and insulin resistance, could spur changes in the brain. Alisa Hrustic, SELF, 24 Mar. 2025 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 3 Jun. 2025.

Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
Last Updated: - Updated example sentences
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