Huntington's disease
noun
Note: Huntington's disease is inherited as an autosomal dominant trait requiring only one parent to pass on a copy of the defective gene on a chromosome other than a sex chromosome. While it may have an onset at any age, people most often become symptomatic between 30 to 50 years of age. The most common symptoms of Huntington's disease include depression, irritability, mood swings, deficits in memory and concentration, dementia, difficulty in swallowing, jerky movements, and loss of coordination.
Examples of Huntington's disease in a Sentence
Jenna Prestininzi, Freep.com, 25 Sep. 2025
Especially when my father-in-law has Huntington's disease and dementia.
—Christina Dugan Ramirez , Tracy Wright, FOXNews.com, 26 Aug. 2025
People of European descent are more likely to have a family history of Huntington's disease because certain genes that cause the disease are more common.2
How Is It Diagnosed?
—Janelle McSwiggin, Health, 27 July 2025
For decades it's been one of the defining mysteries of Huntington's disease.
—Karen Weintraub, USA TODAY, 16 Jan. 2025
Katy Perry, Orlando Bloom in real estate battle with dying veteran
'Outnumbered' reacts to the yearslong legal battle between an elderly veteran suffering from Huntington's disease and the celebrity power couple in California.
—Caroline Thayer, Fox News, 8 Sep. 2024
Cite this Entry
“Huntington's disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Huntington%27s%20disease. Accessed 31 Oct. 2025.
Copy CitationKids Definition
Huntington's disease
noun
Medical Definition
Huntington's disease
noun
Note: Huntington's disease is inherited as an autosomal dominant trait requiring only one parent to pass on a copy of the defective gene on a chromosome other than a sex chromosome. While it may have an onset at any age, people most often become symptomatic between 30 to 50 years of age. The most common symptoms of Huntington's disease include depression, irritability, mood swings, deficits in memory and concentration, dementia, difficulty in swallowing, jerky movements, and loss of coordination.
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