1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Accurate Energetic Systems, established in 1980, specializes in the creation of high-grade explosives for demolition, according to its website. Kirsten Fiscus, Nashville Tennessean, 15 Oct. 2025 More broadly, JPMorgan, Goldman Sachs, and Citi all said their private credit books were diversified and high-grade. Jim Edwards, Fortune, 15 Oct. 2025 Their only hope of survival is to locate a high-grade source of the essential element to repair their ailing vessel. Jeff Spry, Space.com, 13 Oct. 2025 His medical team later described the cancer as high-grade, with a Gleason Score of 9 (Grade Group 5) and signs of metastasis. Samantha-Jo Roth, The Washington Examiner, 11 Oct. 2025 See All Example Sentences for high-grade

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 24 Oct. 2025.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Last Updated: - Updated example sentences
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