differentiation

noun

dif·​fer·​en·​ti·​a·​tion ˌdi-fə-ˌren(t)-shē-ˈā-shən How to pronounce differentiation (audio)
1
: the act or process of differentiating
2
: development from the one to the many, the simple to the complex, or the homogeneous to the heterogeneous
differentiation of Latin into vernaculars
3
biology
a
: modification of body parts for performance of particular functions
b
: the sum of the processes whereby apparently indifferent (see indifferent sense 7) or unspecialized cells, tissues, and structures attain their adult form and function
4
geology : the processes by which various rock types are produced from a common magma

Examples of differentiation in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These are still critical ingredients to creating differentiation and competitive advantage. Fortune Editors, Fortune, 22 Oct. 2025 The company has also created autonomous solutions that reduce its business cyclicality and drive differentiation. Lisa Kailai Han, CNBC, 22 Oct. 2025 The Oscar-winning actress wore an ensemble from Dior’s spring 2026 ready-to-wear collection, which made textural differentiation and contrast its main motif. Julia Teti, Footwear News, 20 Oct. 2025 Due to this visual differentiation, TENCEL™ has typically been used predominantly in weft applications, making up the interior weave of a garment. Carved, Sourcing Journal, 8 Oct. 2025 See All Example Sentences for differentiation

Word History

Etymology

borrowed from New Latin differentiātiōn-, differentiātiō, from Medieval Latin differentiāre "to distinguish, differentiate" + Latin -tiōn-, -tiō, suffix of verbal action

First Known Use

1776, in the meaning defined at sense 1

Time Traveler
The first known use of differentiation was in 1776

Browse Nearby Words

Cite this Entry

“Differentiation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/differentiation. Accessed 29 Oct. 2025.

Kids Definition

differentiation

noun
dif·​fer·​en·​ti·​a·​tion ˌdif-ə-ˌren-chē-ˈā-shən How to pronounce differentiation (audio)
1
: the act or process of differentiating
2
: the processes by which cells and tissues develop their specialized adult form and function
also : the result of these processes

Medical Definition

differentiation

noun
dif·​fer·​en·​ti·​a·​tion -ˌren-chē-ˈā-shən How to pronounce differentiation (audio)
1
a
: the act of describing a thing by giving its differentia
b
: the enhancement of microscopically visible differences between tissue or cell parts by partial selective decolorization or removal of excess stain (as in regressive staining)
c
: the development of a discriminating conditioned response with a positive response to one stimulus and absence of the response on the application of similar but discriminably different stimuli
2
a
: modification of different parts of the body for performance of particular functions
also : specialization of parts or organs in the course of evolution
b
: the sum of the developmental processes whereby apparently unspecialized cells, tissues, and structures attain their adult form and function compare determination sense 2
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