cytosine

noun

cy·​to·​sine ˈsī-tə-ˌsēn How to pronounce cytosine (audio)
: a pyrimidine base C4H5N3O that codes genetic information in the polynucleotide chain of DNA or RNA compare adenine, guanine, thymine, uracil

Examples of cytosine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Biology’s four bases—adenine (A), thymine (T), cytosine (C) and guanine (G)—encode the instructions that keep life alive. Andrew Whalen, Forbes.com, 9 July 2025 In the second set of experiments, the researchers used the targeting and guide RNAs of the CRISPR/Cas system, but linked them to a protein called a cytosine base editor. John Timmer, Ars Technica, 4 Mar. 2025 The most common way of doing this is to link a single carbon atom (a methyl group) to the base cytosine. ArsTechnica, 23 June 2025 This protein essentially lops a small part of the DNA base cytosine, or C, converting it into a thymidine, or T. That can introduce smaller and more specific mutations than CRISPR/Cas. John Timmer, Ars Technica, 4 Mar. 2025 See All Example Sentences for cytosine

Word History

Etymology

International Scientific Vocabulary cyt- + -ose + -ine entry 2

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of cytosine was in 1894

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Cite this Entry

“Cytosine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cytosine. Accessed 18 Jul. 2025.

Kids Definition

cytosine

noun
cy·​to·​sine ˈsīt-ə-ˌsēn How to pronounce cytosine (audio)
: a chemical base that is a pyrimidine and codes genetic information in DNA and RNA compare adenine, guanine, thymine, uracil

Medical Definition

cytosine

noun
cy·​to·​sine ˈsīt-ə-ˌsēn How to pronounce cytosine (audio)
: a pyrimidine base C4H5N3O that codes genetic information in the polynucleotide chain of DNA or RNA compare adenine, guanine, thymine, uracil

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