an·ti·de·pres·sant
ˌan-tē-di-ˈpre-sᵊnt 
ˌan-ˌtī-
ˌan-ˌtī-
: used or tending to relieve or prevent depression
antidepressant drugs
: an antidepressant drug see ssri, tricyclic antidepressant
Examples of antidepressant in a Sentence
Recent Examples on the Web
Joshua Siskin, Oc Register, 25 Oct. 2025
Every commercial break in this game should be nothing but antidepressant ads.
—J.j. Bailey, New York Times, 19 Oct. 2025
Tanya Lewis, Scientific American, 23 Oct. 2025
Tyramine can suddenly raise blood pressure when combined with monoamine oxidase inhibitors (MAOIs), a type of antidepressant.
—Merve Ceylan, Health, 20 Oct. 2025
See All Example Sentences for antidepressant
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Adjective
It is used as a dye, to enhance flavor in a variety of foods, for incense fragrance, and as an antidepressant tea.
—Joshua Siskin, Oc Register, 25 Oct. 2025
Every commercial break in this game should be nothing but antidepressant ads.
—J.j. Bailey, New York Times, 19 Oct. 2025
Noun
Over the summer the FDA convened a panel on the safety of certain antidepressants in pregnancy that tried to cast doubt on this research, ignoring the real harms of not treating depression or anxiety for pregnant people themselves and for their fetuses.
—Tanya Lewis, Scientific American, 23 Oct. 2025
Tyramine can suddenly raise blood pressure when combined with monoamine oxidase inhibitors (MAOIs), a type of antidepressant.
—Merve Ceylan, Health, 20 Oct. 2025
See All Example Sentences for antidepressant
Cite this Entry
“Antidepressant.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antidepressant. Accessed 29 Oct. 2025.
Copy CitationMedical Definition
antidepressant
1 of 2 adjective
an·ti·de·pres·sant
ˌant-i-di-ˈpres-ᵊnt, ˌan-ˌtī-
variants
also antidepressive
: used or tending to relieve or prevent psychological depression : relating to, being, or utilizing an antidepressant
an antidepressant drug
antidepressant treatment
antidepressant
2 of 2 noun
variants
also antidepressive
: a drug used to treat psychological depression : an antidepressant drug
The dual-action antidepressant venlafaxine appears to demonstrate superior efficacy and higher rates of remission in severe depression as compared with either SSRIs such as fluoxetine or tricyclic antidepressants.—John Mann, The New England Journal of Medicine
John Mann, The New England Journal of Medicinecalled also energizer, psychic energizer, psychostimulant
see tricyclic antidepressantLove words? Need even more definitions?
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