: either of two physiologically active isomers C21H30O2 from hemp plant resin
especially : one that is the chief intoxicant in marijuana
When a person tokes, eats or vapes cannabis, a wave of THC, or tetrahydrocannabinol, washes into the brain. Laura Sanders
THC, the main chemical component of marijuana, has been shown to reduce nausea and increase appetite in chemotherapy patients. Andrew Weil
THC disappears from blood quickly as it is absorbed in the brain, making blood tests a more reliable measure of recent use but not a great correlate of impairment. Eliza Gray

Examples of THC in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
There was no movement on setting limits for THC potency, no requirement to test for contamination and no mandate to keep these products out of the hands of minors. Brian Hopkins, Chicago Tribune, 14 July 2025 The committee is now closing this loophole by proposing a bill that would prohibit all products containing any quantifiable amount of THC. Dario Sabaghi, Forbes.com, 11 July 2025 Many of the products contain delta-8, an isomer of THC, the main psychoactive compound found in marijuana. arkansasonline.com, 9 July 2025 Hemp is a type of cannabis plant with low levels of the psychoactive compound that gets people high, known as delta-9 THC. Alison Dirr, jsonline.com, 7 July 2025 See All Example Sentences for THC

Word History

Etymology

tetrahydrocannabinol

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of THC was in 1967

Browse Nearby Words

Cite this Entry

“THC.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/THC. Accessed 18 Jul. 2025.

Medical Definition

: either of two physiologically active isomers C21H30O2 that occur naturally in hemp plant resin or are synthetically prepared:
a
: one that is the chief intoxicant in marijuana and is used medicinally

called also delta-9-tetrahydrocannabinol, delta-9-THC

see dronabinol
b
: one that is present in marijuana only in minute quantities

More from Merriam-Webster on THC

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